Skip to content Skip to sidebar Skip to footer
Home / Can Covid Cause Low White Blood Cell Count

Can Covid Cause Low White Blood Cell Count

Post a Comment

. 2022 February;44(ane):104-111.

doi: ten.1111/ijlh.13728. Epub 2022 Oct 8.

Diagnostic value of white blood jail cell parameters for COVID-nineteen: Is there a role for HFLC and IG?

Affiliations

  • PMID: 34623763
  • PMCID: PMC8653118
  • DOI: 10.1111/ijlh.13728

Free PMC article

Diagnostic value of white blood jail cell parameters for COVID-nineteen: Is there a role for HFLC and IG?

Alexandra Myari  et al. Int J Lab Hematol. 2022 Feb .

Gratuitous PMC article

Abstruse

Introduction: As the Coronavirus disease 2022 (COVID-19) pandemic is nonetheless ongoing with patients overwhelming healthcare facilities, nosotros aimed to investigate the ability of white claret cell count (WBC) and their subsets, high fluorescence lymphocyte cells (HFLC), young granulocyte count (IG), and C-reactive protein (CRP) to assist diagnosis of COVID-19 during the triage process and every bit indicators of affliction progression to serious and critical condition.

Methods: We collected clinical and laboratory data of patients, suspected COVID-19 cases, admitted at the emergency section of Academy Full general Infirmary of Ioannina (Ioannina, Greece). Nosotros selected 197 negative and 368 positive cases, confirmed past polymerase chain reaction test for astringent acute respiratory syndrome coronavirus 2. COVID-19 cases were classified into mild, serious, and critical illness. Receiver operating characteristic curve and binary logistic regression analysis were utilized for assessing the diagnosing ability of biomarkers.

Results: WBC, neutrophil count (NEUT), and HFLC can discriminate efficiently negative cases from mild and serious COVID-19, whereas eosinopenia and basopenia are early indicators of the illness. The combined WBC-HFLC marker is the all-time diagnostic mark for both mild (sensitivity: 90.6% and specificity: 64.1%) and serious (sensitivity: xc.3% and specificity: 73.4%) disease. CRP and Lymphocyte count are early on indicators of progression to serious illness whereas WBC, NEUT, IG, and neutrophil-to-lymphocyte ratio are the all-time indicators of critical affliction.

Decision: Lymphopenia is not useful in screening patients with COVID-nineteen. HFLC is a skillful diagnostic marking for balmy and serious illness either every bit a single marker or combined with WBC whereas IG is a good indicator of progression to critical disease.

Keywords: COVID-19; biomarkers; diagnosis; leukocytes; statistic.

Conflict of interest argument

The authors have no competing interests.

Figures

FIGURE 1
FIGURE 1

Patient period chart

Similar manufactures

  • Routine laboratory testing to decide if a patient has COVID-19.

    Stegeman I, Ochodo EA, Guleid F, Holtman GA, Yang B, Davenport C, Deeks JJ, Dinnes J, Dittrich South, Emperador D, Hooft L, Spijker R, Takwoingi Y, Van den Bruel A, Wang J, Langendam M, Verbakel JY, Leeflang MM; Cochrane COVID-19 Diagnostic Test Accuracy Group. Stegeman I, et al. Cochrane Database Syst Rev. 2022 Nov 19;xi(eleven):CD013787. doi: ten.1002/14651858.CD013787. Cochrane Database Syst Rev. 2020. PMID: 33211319 Gratuitous PMC article.

  • Utility of the neutrophil-to-lymphocyte ratio and C-reactive protein level for coronavirus illness 2022 (COVID-19).

    Yufei Y, Mingli L, Xuejiao 50, Xuemei D, Yiming J, Qin Q, Hui S, Jie G. Yufei Y, et al. Scand J Clin Lab Invest. 2022 Nov;80(7):536-540. doi: 10.1080/00365513.2020.1803587. Epub 2022 Aug 17. Scand J Clin Lab Invest. 2020. PMID: 32804580 Free PMC article.

  • Immunity and coagulation and fibrinolytic processes may reduce the adventure of severe illness in meaning women with coronavirus disease 2019.

    Zhong Y, Cao Y, Zhong X, Peng Z, Jiang South, Tang T, Chen H, Li X, Xia Y, Cheng Y, Zhao X. Zhong Y, et al. Am J Obstet Gynecol. 2022 Apr;224(iv):393.e1-393.e25. doi: ten.1016/j.ajog.2020.10.032. Epub 2022 Oct 22. Am J Obstet Gynecol. 2021. PMID: 33098813 Gratuitous PMC commodity.

  • Study on Laboratory Indicators Related to Lung Injury of Corona Virus Illness 2019.

    Zhang Y, Chen Q, Yao L, Chen J, Yu X. Zhang Y, et al. Clin Lab. 2022 Jan 1;67(ane). doi: ten.7754/Clin.Lab.2020.200606. Clin Lab. 2021. PMID: 33491433

  • Differences of inflammatory and non-inflammatory indicators in Coronavirus disease-19 (COVID-19) with unlike severity.

    Wang M, Zhu Q, Fu J, Liu 50, Xiao M, Du Y. Wang M, et al. Infect Genet Evol. 2022 Nov;85:104511. doi: 10.1016/j.meegid.2020.104511. Epub 2022 Aug 26. Infect Genet Evol. 2020. PMID: 32858231 Gratuitous PMC article.

References

    1. https://covid19.who.int/. Accessed 3 May, 2021.
    1. https://world wide web.ecdc.europa.european union/sites/default/files/documents/COVID‐nineteen‐risk‐r.... Accessed 3 May, 2021
    1. Ferrari D, Motta A, Strollo K, Banfi Thou, Locatelli M. Routine claret tests as a potential diagnostic tool for COVID‐19. Clin Chem Lab Med. 2020;58:1095‐1099. - PubMed
    1. Yun H, Sun Z, Wu J, Tang A, Hu M, Xiang Z. Laboratory data assay of novel coronavirus (COVID‐nineteen) screening in 2510 patients. Clin Chim Acta. 2020;507:94‐97. - PMC - PubMed
    1. Tan Y, Zhou J, Zhou Q, Hu Fifty, Long Y. Role of eosinophils in the diagnosis and prognostic evaluation of COVID‐19. J Med Virol. 2021;93:1105‐1110. - PubMed

MeSH terms

Substances

LinkOut - more resources

  • Full Text Sources

    • Europe PubMed Key
    • Ovid Technologies, Inc.
    • PubMed Primal
    • Wiley

  • Medical

    • MedlinePlus Health Data

  • Research Materials

    • NCI CPTC Antibody Characterization Program

  • Miscellaneous

    • NCI CPTAC Assay Portal

summershicientich.blogspot.com

Source: https://pubmed.ncbi.nlm.nih.gov/34623763/

You may like these posts

Post a Comment for "Can Covid Cause Low White Blood Cell Count"